Cloning and high-level expression of monomeric human superoxide dismutase 1 (SOD1) and its interaction with pyrimidine analogs

Superoxide dismutase 1 (SOD1) is known to be involved in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS) and is therefore considered to be an important ALS drug target. Identifying potential drug leads that bind to SOD1 and characterizing their interactions by nuclear magnetic resonance (NMR...

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Detalles Bibliográficos
Autores principales: LeVatte, Marcia, Lipfert, Matthias, Roy, Dipankar, Kovalenko, Andriy, Wishart, David Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909654/
https://www.ncbi.nlm.nih.gov/pubmed/33635895
http://dx.doi.org/10.1371/journal.pone.0247684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909654/
https://www.ncbi.nlm.nih.gov/pubmed/33635895
http://dx.doi.org/10.1371/journal.pone.0247684

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