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Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model

Neisseria meningitidis (the meningococcus) remains a major cause of bacterial meningitis and fatal sepsis. This commensal bacterium of the human nasopharynx can cause invasive diseases when it leaves its niche and reaches the bloodstream. Blood-borne meningococci have the ability to adhere to human...

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Detalles Bibliográficos
Autores principales: Barnier, Jean-Philippe, Euphrasie, Daniel, Join-Lambert, Olivier, Audry, Mathilde, Schonherr-Hellec, Sophia, Schmitt, Taliah, Bourdoulous, Sandrine, Coureuil, Mathieu, Nassif, Xavier, El Behi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909687/
https://www.ncbi.nlm.nih.gov/pubmed/33592056
http://dx.doi.org/10.1371/journal.ppat.1009299