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Computational prediction of drug response in short QT syndrome type 1 based on measurements of compound effect in stem cell-derived cardiomyocytes

Short QT (SQT) syndrome is a genetic cardiac disorder characterized by an abbreviated QT interval of the patient’s electrocardiogram. The syndrome is associated with increased risk of arrhythmia and sudden cardiac death and can arise from a number of ion channel mutations. Cardiomyocytes derived fro...

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Detalles Bibliográficos
Autores principales: Jæger, Karoline Horgmo, Wall, Samuel, Tveito, Aslak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909705/
https://www.ncbi.nlm.nih.gov/pubmed/33591962
http://dx.doi.org/10.1371/journal.pcbi.1008089