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Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia

Congenital eye defects represent a large class of disorders affecting roughly 21 million children worldwide. Microphthalmia and anophthalmia are relatively common congenital defects, with approximately 20% of human cases caused by mutations in SOX2. Recently, we identified the RNA-binding motif prot...

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Detalles Bibliográficos
Autores principales: Brastrom, Lindy K., Scott, C. Anthony, Wang, Kai, Slusarski, Diane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909789/
https://www.ncbi.nlm.nih.gov/pubmed/33494192
http://dx.doi.org/10.3390/biomedicines9020100