Cargando…
Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia
Congenital eye defects represent a large class of disorders affecting roughly 21 million children worldwide. Microphthalmia and anophthalmia are relatively common congenital defects, with approximately 20% of human cases caused by mutations in SOX2. Recently, we identified the RNA-binding motif prot...
Autores principales: | Brastrom, Lindy K., Scott, C. Anthony, Wang, Kai, Slusarski, Diane C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909789/ https://www.ncbi.nlm.nih.gov/pubmed/33494192 http://dx.doi.org/10.3390/biomedicines9020100 |
Ejemplares similares
-
A High-Throughput Assay for Congenital and Age-Related Eye Diseases in Zebrafish
por: Brastrom, Lindy K., et al.
Publicado: (2019) -
Rbm24a and Rbm24b Are Required for Normal Somitogenesis
por: Maragh, Samantha, et al.
Publicado: (2014) -
RNA‐binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA
por: Xia, Rong Mu, et al.
Publicado: (2021) -
Targeted 'Next-Generation' sequencing in anophthalmia and microphthalmia patients confirms SOX2, OTX2 and FOXE3 mutations
por: Lopez Jimenez, Nelson, et al.
Publicado: (2011) -
Anophthalmia and microphthalmia
por: Verma, Amit S, et al.
Publicado: (2007)