Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver

Ionizable lipid nanoparticles (LNPs) have been widely used for in vivo delivery of RNA therapeutics into the liver. However, a main challenge remains to develop LNP formulations for selective delivery of RNA into certain types of liver cells, such as hepatocytes and liver sinusoidal endothelial cell...

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Detalles Bibliográficos
Autores principales: Kim, M., Jeong, M., Hur, S., Cho, Y., Park, J., Jung, H., Seo, Y., Woo, H. A., Nam, K. T., Lee, K., Lee, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909888/
https://www.ncbi.nlm.nih.gov/pubmed/33637537
http://dx.doi.org/10.1126/sciadv.abf4398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909888/
https://www.ncbi.nlm.nih.gov/pubmed/33637537
http://dx.doi.org/10.1126/sciadv.abf4398

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