Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity

The innate immune response influences neural repair after spinal cord injury (SCI). Here, we combined myeloid-specific transcriptomics and single-cell RNA sequencing to uncover not only a common core but also temporally distinct gene programs in injury-activated microglia and macrophages (IAM). Intr...

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Detalles Bibliográficos
Autores principales: Wahane, Shalaka, Zhou, Xianxiao, Zhou, Xiang, Guo, Lei, Friedl, Marie-Sophie, Kluge, Michael, Ramakrishnan, Aarthi, Shen, Li, Friedel, Caroline C., Zhang, Bin, Friedel, Roland H., Zou, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909890/
https://www.ncbi.nlm.nih.gov/pubmed/33637528
http://dx.doi.org/10.1126/sciadv.abd8811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909890/
https://www.ncbi.nlm.nih.gov/pubmed/33637528
http://dx.doi.org/10.1126/sciadv.abd8811

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