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Inhibitory efficacy of RNA virus drugs against SARS-CoV-2 proteins: An extensive study

Herein we have made a comprehensive analysis of inhibitory efficacy of 16 RNA virus drugs against RdRp, Mpro and PLpro proteins of SARS-CoV-2. Analysis of docked conformation revealed that Baloxavir marboxil (BMX) corresponds to the highest binding energy. Analysis of residue confirmed that BMX stro...

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Detalles Bibliográficos
Autores principales: Mandal, Manab, Chowdhury, Swapan Kumar, Khan, Abdul Ashik, Baildya, Nabajyoti, Dutta, Tanmoy, Misra, Debabrata, Ghosh, Narendra Nath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909904/
https://www.ncbi.nlm.nih.gov/pubmed/33678903
http://dx.doi.org/10.1016/j.molstruc.2021.130152