Interleukin-1β-Treated Mesenchymal Stem Cells Inhibit Inflammation in Hippocampal Astrocytes Through Exosome-Activated Nrf-2 Signaling

BACKGROUND: Interleukin-1β (IL-1)-treated mesenchymal stem cells (MSCs) and IL-1-MSCs-conditioned medium (CM) exert anti-inflammatory roles. Astrocytes are essential for the modulation of synaptic activity and neuronal homeostasis in the brain. Exosomes are the critical mediators in intercellular co...

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Detalles Bibliográficos
Autores principales: Liu, Kai, Cai, Guo-Liang, Zhuang, Zhe, Pei, Si-Ying, Xu, Sheng-Nan, Wang, Ya-Nan, Wang, Hong, Wang, Xin, Cui, Cheng, Sun, Man-Chao, Guo, Si-Hui, Jia, Kun-Ping, Wang, Xiu-Zhen, Cai, Guo-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910114/
https://www.ncbi.nlm.nih.gov/pubmed/33654394
http://dx.doi.org/10.2147/IJN.S289914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910114/
https://www.ncbi.nlm.nih.gov/pubmed/33654394
http://dx.doi.org/10.2147/IJN.S289914

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