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Interleukin-1β-Treated Mesenchymal Stem Cells Inhibit Inflammation in Hippocampal Astrocytes Through Exosome-Activated Nrf-2 Signaling

BACKGROUND: Interleukin-1β (IL-1)-treated mesenchymal stem cells (MSCs) and IL-1-MSCs-conditioned medium (CM) exert anti-inflammatory roles. Astrocytes are essential for the modulation of synaptic activity and neuronal homeostasis in the brain. Exosomes are the critical mediators in intercellular co...

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Detalles Bibliográficos
Autores principales:	Liu, Kai, Cai, Guo-Liang, Zhuang, Zhe, Pei, Si-Ying, Xu, Sheng-Nan, Wang, Ya-Nan, Wang, Hong, Wang, Xin, Cui, Cheng, Sun, Man-Chao, Guo, Si-Hui, Jia, Kun-Ping, Wang, Xiu-Zhen, Cai, Guo-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910114/ https://www.ncbi.nlm.nih.gov/pubmed/33654394 http://dx.doi.org/10.2147/IJN.S289914

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