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5-Azacytidine restores interleukin 6-increased production in mesenchymal stromal cells from myelodysplastic patients

INTRODUCTION: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological diseases. In addition to defects in hematologic progenitor and stem cells, dysfunctions in the bone marrow microenvironment (BMM) participate in the MDS pathogenesis. Furthermore, the immune response is d...

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Detalles Bibliográficos
Autores principales: Boada, Matilde, Echarte, Lourdes, Guillermo, Cecilia, Diaz, Lilián, Touriño, Cristina, Grille, Sofía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910176/
https://www.ncbi.nlm.nih.gov/pubmed/32008984
http://dx.doi.org/10.1016/j.htct.2019.12.002