Combined cellomics and proteomics analysis reveals shared neuronal morphology and molecular pathway phenotypes for multiple schizophrenia risk genes

An enigma in studies of neuropsychiatric disorders is how to translate polygenic risk into disease biology. For schizophrenia, where > 145 significant GWAS loci have been identified and only a few genes directly implicated, addressing this issue is a particular challenge. We used a combined cello...

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Detalles Bibliográficos
Autores principales: Rosato, Martina, Stringer, Sven, Gebuis, Titia, Paliukhovich, Iryna, Li, Ka Wan, Posthuma, Danielle, Sullivan, Patrick F., Smit, August B., van Kesteren, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910218/
https://www.ncbi.nlm.nih.gov/pubmed/31142819
http://dx.doi.org/10.1038/s41380-019-0436-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910218/
https://www.ncbi.nlm.nih.gov/pubmed/31142819
http://dx.doi.org/10.1038/s41380-019-0436-y

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