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Human Biodistribution and Radiation Dosimetry of the P-Glycoprotein Radiotracer [(11)C]Metoclopramide

PURPOSE: To assess in healthy volunteers the whole-body distribution and dosimetry of [(11)C]metoclopramide, a new positron emission tomography (PET) tracer to measure P-glycoprotein activity at the blood-brain barrier. PROCEDURES: Ten healthy volunteers (five women, five men) were intravenously inj...

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Detalles Bibliográficos
Autores principales: Bauer, Martin, Barna, Sandra, Blaickner, Matthias, Prosenz, Konstantin, Bamminger, Karsten, Pichler, Verena, Tournier, Nicolas, Hacker, Marcus, Zeitlinger, Markus, Karanikas, Georgios, Langer, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910245/
https://www.ncbi.nlm.nih.gov/pubmed/33481175
http://dx.doi.org/10.1007/s11307-021-01582-4