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LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival

Mitochondrial proteases are key components in mitochondrial stress responses that maintain proteostasis and mitochondrial integrity in harsh environmental conditions, which leads to the acquisition of aggressive phenotypes, including chemoresistance and metastasis. However, the molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Lee, Yu Geon, Kim, Hui Won, Nam, Yeji, Shin, Kyeong Jin, Lee, Yu Jin, Park, Do Hong, Rhee, Hyun-Woo, Seo, Jeong Kon, Chae, Young Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910295/
https://www.ncbi.nlm.nih.gov/pubmed/33637676
http://dx.doi.org/10.1038/s41389-021-00306-1