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LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival
Mitochondrial proteases are key components in mitochondrial stress responses that maintain proteostasis and mitochondrial integrity in harsh environmental conditions, which leads to the acquisition of aggressive phenotypes, including chemoresistance and metastasis. However, the molecular mechanisms...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910295/ https://www.ncbi.nlm.nih.gov/pubmed/33637676 http://dx.doi.org/10.1038/s41389-021-00306-1 |