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LRP1 mediates the IGF-1-induced GLUT1 expression on the cell surface and glucose uptake in Müller glial cells

Insulin-like Growth Factor-1 (IGF-1) is involved in the normal development and survival of retinal cells. Low-density lipoprotein Receptor-related Protein-1 (LRP1) plays a key role on the regulation of several membrane proteins, such as the IGF-1 receptor (IGF-1R). In brain astrocytes, LRP1 interact...

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Detalles Bibliográficos
Autores principales: Actis Dato, Virginia, Sánchez, María Cecilia, Chiabrando, Gustavo Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910306/
https://www.ncbi.nlm.nih.gov/pubmed/33637845
http://dx.doi.org/10.1038/s41598-021-84090-3