Melanoma brain metastases have lower T-cell content and microvessel density compared to matched extracranial metastases

BACKGROUND: Although melanoma brain metastases (MBM) tend to respond to systemic therapy concordantly with extracranial metastases, little is known about differences in immune cell and vascular content between the brain and other metastatic sites. Here we studied infiltrating immune cell subsets and...

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Detalles Bibliográficos
Autores principales: Weiss, Sarah A., Zito, Christopher, Tran, Thuy, Heishima, Kazuki, Neumeister, Veronique, McGuire, John, Adeniran, Adebowale, Kluger, Harriet, Jilaveanu, Lucia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Laboratory Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910371/
https://www.ncbi.nlm.nih.gov/pubmed/32974852
http://dx.doi.org/10.1007/s11060-020-03619-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910371/
https://www.ncbi.nlm.nih.gov/pubmed/32974852
http://dx.doi.org/10.1007/s11060-020-03619-0

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