Design of PSMA ligands with modifications at the inhibitor part: an approach to reduce the salivary gland uptake of radiolabeled PSMA inhibitors?

AIM: To investigate whether modifications of prostate-specific membrane antigen (PSMA)-targeted radiolabeled urea-based inhibitors could reduce salivary gland uptake and thus improve tumor-to-salivary gland ratios, several analogs of a high affinity PSMA ligand were synthesized and evaluated in in v...

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Detalles Bibliográficos
Autores principales: Felber, Veronika Barbara, Valentin, Manuel Amando, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910394/
https://www.ncbi.nlm.nih.gov/pubmed/33638060
http://dx.doi.org/10.1186/s41181-021-00124-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910394/
https://www.ncbi.nlm.nih.gov/pubmed/33638060
http://dx.doi.org/10.1186/s41181-021-00124-1

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