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PlasmidHawk improves lab of origin prediction of engineered plasmids using sequence alignment

With advances in synthetic biology and genome engineering comes a heightened awareness of potential misuse related to biosafety concerns. A recent study employed machine learning to identify the lab-of-origin of DNA sequences to help mitigate some of these concerns. Despite their promising results,...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Kille, Bryce, Liu, Tian Rui, Elworth, R. A. Leo, Treangen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910462/
https://www.ncbi.nlm.nih.gov/pubmed/33637701
http://dx.doi.org/10.1038/s41467-021-21180-w