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Retroviral integrations contribute to elevated host cancer rates during germline invasion

Repeated retroviral infections of vertebrate germlines have made endogenous retroviruses ubiquitous features of mammalian genomes. However, millions of years of evolution obscure many of the immediate repercussions of retroviral endogenisation on host health. Here we examine retroviral endogenisatio...

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Detalles Bibliográficos
Autores principales: McEwen, Gayle K., Alquezar-Planas, David E., Dayaram, Anisha, Gillett, Amber, Tarlinton, Rachael, Mongan, Nigel, Chappell, Keith J., Henning, Joerg, Tan, Milton, Timms, Peter, Young, Paul R., Roca, Alfred L., Greenwood, Alex D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910482/
https://www.ncbi.nlm.nih.gov/pubmed/33637755
http://dx.doi.org/10.1038/s41467-021-21612-7