Bayesian optimization for estimating the maximum tolerated dose in Phase I clinical trials

We introduce a Bayesian optimization method for estimating the maximum tolerated dose in this article. A number of parametric model-based methods have been proposed to estimate the maximum tolerated dose; however, parametric model-based methods need an assumption that dose–toxicity relationships fol...

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Detalles Bibliográficos
Autores principales: Takahashi, Ami, Suzuki, Taiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910500/
https://www.ncbi.nlm.nih.gov/pubmed/33681528
http://dx.doi.org/10.1016/j.conctc.2021.100753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910500/
https://www.ncbi.nlm.nih.gov/pubmed/33681528
http://dx.doi.org/10.1016/j.conctc.2021.100753

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