Cargando…
Bayesian optimization for estimating the maximum tolerated dose in Phase I clinical trials
We introduce a Bayesian optimization method for estimating the maximum tolerated dose in this article. A number of parametric model-based methods have been proposed to estimate the maximum tolerated dose; however, parametric model-based methods need an assumption that dose–toxicity relationships fol...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910500/ https://www.ncbi.nlm.nih.gov/pubmed/33681528 http://dx.doi.org/10.1016/j.conctc.2021.100753 |