Autophagy-enhancing drugs limit mucosal HIV-1 acquisition and suppress viral replication ex vivo

Current direct-acting antiviral therapies are highly effective in suppressing HIV-1 replication. However, mucosal inflammation undermines prophylactic treatment efficacy, and HIV-1 persists in long-lived tissue-derived dendritic cells (DCs) and CD4(+) T cells of treated patients. Host-directed strat...

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Detalles Bibliográficos
Autores principales: Cloherty, Alexandra P. M., van Teijlingen, Nienke H., Eisden, Tracy-Jane T. H. D., van Hamme, John L., Rader, Anusca G., Geijtenbeek, Teunis B. H., Schreurs, Renée R. C. E., Ribeiro, Carla M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910550/
https://www.ncbi.nlm.nih.gov/pubmed/33637808
http://dx.doi.org/10.1038/s41598-021-84081-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910550/
https://www.ncbi.nlm.nih.gov/pubmed/33637808
http://dx.doi.org/10.1038/s41598-021-84081-4

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