Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp(3))-H olefination mediated by donor/donor carbenes

Biomimetic modularization and function-oriented synthesis of structurally diversified natural product-like macrocycles in a step-economical fashion is highly desirable. Inspired by marine furanocembranoids, herein, we synthesize diverse alkenes substituted furan-embedded macrolactams via a modular b...

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Detalles Bibliográficos
Autores principales: Hao, Jiping, Guo, Xueying, He, Shijun, Xu, Zhongliang, Chen, Lu, Li, Zhongyu, Song, Bichao, Zuo, Jianping, Lin, Zhenyang, Yang, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910576/
https://www.ncbi.nlm.nih.gov/pubmed/33637703
http://dx.doi.org/10.1038/s41467-021-21484-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910576/
https://www.ncbi.nlm.nih.gov/pubmed/33637703
http://dx.doi.org/10.1038/s41467-021-21484-x

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