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Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp(3))-H olefination mediated by donor/donor carbenes
Biomimetic modularization and function-oriented synthesis of structurally diversified natural product-like macrocycles in a step-economical fashion is highly desirable. Inspired by marine furanocembranoids, herein, we synthesize diverse alkenes substituted furan-embedded macrolactams via a modular b...
Autores principales: | Hao, Jiping, Guo, Xueying, He, Shijun, Xu, Zhongliang, Chen, Lu, Li, Zhongyu, Song, Bichao, Zuo, Jianping, Lin, Zhenyang, Yang, Weibo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910576/ https://www.ncbi.nlm.nih.gov/pubmed/33637703 http://dx.doi.org/10.1038/s41467-021-21484-x |
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