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Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice

Obesity is caused by a long-term imbalance between energy intake and consumption and is regulated by multiple signals. This study investigated the effect of signaling scaffolding protein Gab2 on obesity and its relevant regulation mechanism. Gab2 knockout (KO) and wild-type (WT) mice were fed with a...

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Detalles Bibliográficos
Autores principales: Wang, Xinhui, Zhao, Yinan, Zhou, Dekun, Tian, Yingpu, Feng, Gensheng, Lu, Zhongxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910586/
https://www.ncbi.nlm.nih.gov/pubmed/33637697
http://dx.doi.org/10.1038/s41419-021-03519-9