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Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice
Obesity is caused by a long-term imbalance between energy intake and consumption and is regulated by multiple signals. This study investigated the effect of signaling scaffolding protein Gab2 on obesity and its relevant regulation mechanism. Gab2 knockout (KO) and wild-type (WT) mice were fed with a...
Autores principales: | Wang, Xinhui, Zhao, Yinan, Zhou, Dekun, Tian, Yingpu, Feng, Gensheng, Lu, Zhongxian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910586/ https://www.ncbi.nlm.nih.gov/pubmed/33637697 http://dx.doi.org/10.1038/s41419-021-03519-9 |
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