System-wide identification and prioritization of enzyme substrates by thermal analysis

Despite the immense importance of enzyme–substrate reactions, there is a lack of general and unbiased tools for identifying and prioritizing substrate proteins that are modified by the enzyme on the structural level. Here we describe a high-throughput unbiased proteomics method called System-wide Id...

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Detalles Bibliográficos
Autores principales: Saei, Amir Ata, Beusch, Christian M., Sabatier, Pierre, Wells, Juan Astorga, Gharibi, Hassan, Meng, Zhaowei, Chernobrovkin, Alexey, Rodin, Sergey, Näreoja, Katja, Thorsell, Ann-Gerd, Karlberg, Tobias, Cheng, Qing, Lundström, Susanna L., Gaetani, Massimiliano, Végvári, Ákos, Arnér, Elias S. J., Schüler, Herwig, Zubarev, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910609/
https://www.ncbi.nlm.nih.gov/pubmed/33637753
http://dx.doi.org/10.1038/s41467-021-21540-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910609/
https://www.ncbi.nlm.nih.gov/pubmed/33637753
http://dx.doi.org/10.1038/s41467-021-21540-6

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