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Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses

Enteroviruses pose a persistent and widespread threat to human physical health, with no specific treatments available. Small molecule capsid binders have the potential to be developed as antivirals that prevent virus attachment and entry into host cells. To aid with broad-range drug development, we...

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Detalles Bibliográficos
Autores principales: Flatt, Justin W., Domanska, Aušra, Seppälä, Alma L., Butcher, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910612/
https://www.ncbi.nlm.nih.gov/pubmed/33637854
http://dx.doi.org/10.1038/s42003-021-01779-x