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Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

BACKGROUND: Gut microbiota (GM) contribute to obesity and insulin resistance (IR). Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), promotes IR and alters GM. Since circulating exosomes are implicated in IR, we examined the effects of IH and physical activity (PA) in mice o...

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Detalles Bibliográficos
Autores principales: Khalyfa, Abdelnaby, Ericsson, Aaron, Qiao, Zhuanghong, Almendros, Isaac, Farré, Ramon, Gozal, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910674/
https://www.ncbi.nlm.nih.gov/pubmed/33485839
http://dx.doi.org/10.1016/j.ebiom.2021.103208