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A Multimodal Platform for Simultaneous T-cell Imaging, Defined Activation, and Mechanobiological Characterization

T-cell antigen recognition is accompanied by extensive morphological rearrangements of the contact zone between the T-cell and the antigen-presenting cell (APC). This process involves binding of the T-cell receptor (TCR) complex to antigenic peptides presented via MHC on the APC surface, the interac...

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Detalles Bibliográficos
Autores principales: Fölser, Martin, Motsch, Viktoria, Platzer, René, Huppa, Johannes B., Schütz, Gerhard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910839/
https://www.ncbi.nlm.nih.gov/pubmed/33504075
http://dx.doi.org/10.3390/cells10020235