Fabrication and Appraisal of Simvastatin via Tailored Niosomal Nanovesicles for Transdermal Delivery Enhancement: In Vitro and In Vivo Assessment

Simvastatin (SIM) is a HMG-CoA reductase inhibitor employed in the management of hyperlipidemia. However, its low bioavailability limits its clinical efficacy. The objective of this study was to overcome the poor bioavailability of SIM via the transdermal application of a SIM-loaded niosomal gel. Ni...

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Detalles Bibliográficos
Autores principales: Salem, Heba F., Kharshoum, Rasha M., Abou-Taleb, Heba A., Farouk, Hanan Osman, Zaki, Randa Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910921/
https://www.ncbi.nlm.nih.gov/pubmed/33494472
http://dx.doi.org/10.3390/pharmaceutics13020138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910921/
https://www.ncbi.nlm.nih.gov/pubmed/33494472
http://dx.doi.org/10.3390/pharmaceutics13020138

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