Cargando…

Structural Insights into Substrate Recognition and Processing by the 20S Proteasome

Four decades of proteasome research have yielded extensive information on ubiquitin-dependent proteolysis. The archetype of proteasomes is a 20S barrel-shaped complex that does not rely on ubiquitin as a degradation signal but can degrade substrates with a considerable unstructured stretch. Since ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahu, Indrajit, Glickman, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910952/
https://www.ncbi.nlm.nih.gov/pubmed/33498876
http://dx.doi.org/10.3390/biom11020148