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Structural Insights into Substrate Recognition and Processing by the 20S Proteasome
Four decades of proteasome research have yielded extensive information on ubiquitin-dependent proteolysis. The archetype of proteasomes is a 20S barrel-shaped complex that does not rely on ubiquitin as a degradation signal but can degrade substrates with a considerable unstructured stretch. Since ro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910952/ https://www.ncbi.nlm.nih.gov/pubmed/33498876 http://dx.doi.org/10.3390/biom11020148 |