Cargando…

Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery

The ruthenium polypyridyl complex [Ru(dppz)(2)PIP](2+) (dppz: dipyridophenazine, PIP: (2-(phenyl)-imidazo[4,5-f ][1,10]phenanthroline), or Ru-PIP, is a potential anticancer drug that acts by inhibiting DNA replication. Due to the poor dissolution of Ru-PIP in aqueous media, a drug delivery agent wou...

Descripción completa

Detalles Bibliográficos
Autores principales: Harun, Siti Norain, Ahmad, Haslina, Lim, Hong Ngee, Chia, Suet Lin, Gill, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910993/
https://www.ncbi.nlm.nih.gov/pubmed/33498795
http://dx.doi.org/10.3390/pharmaceutics13020150