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Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery

The ruthenium polypyridyl complex [Ru(dppz)(2)PIP](2+) (dppz: dipyridophenazine, PIP: (2-(phenyl)-imidazo[4,5-f ][1,10]phenanthroline), or Ru-PIP, is a potential anticancer drug that acts by inhibiting DNA replication. Due to the poor dissolution of Ru-PIP in aqueous media, a drug delivery agent wou...

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Detalles Bibliográficos
Autores principales:	Harun, Siti Norain, Ahmad, Haslina, Lim, Hong Ngee, Chia, Suet Lin, Gill, Martin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910993/ https://www.ncbi.nlm.nih.gov/pubmed/33498795 http://dx.doi.org/10.3390/pharmaceutics13020150

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