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Hyaluronidase Inhibitor-Incorporated Cross-Linked Hyaluronic Acid Hydrogels for Subcutaneous Injection

Hyaluronidase (HAase) inhibitor-incorporated hyaluronic acid (HA) hydrogel cross-linked with 1,4-butanediol diglycidyl ether (BDDE) was designed to reduce the toxicity risk induced by BDDE and its biodegradation rate in subcutaneous tissue. The formulation composition of hydrogel and its preparation...

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Detalles Bibliográficos
Autores principales: Kim, Min-Hwan, Park, Ju-Hwan, Nguyen, Duy-Thuc, Kim, Sungyun, Jeong, Da In, Cho, Hyun-Jong, Kim, Dae-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910999/
https://www.ncbi.nlm.nih.gov/pubmed/33513991
http://dx.doi.org/10.3390/pharmaceutics13020170