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Rescuing the Last-Line Polymyxins: Achievements and Challenges

Antibiotic resistance is a major global health challenge and, worryingly, several key Gram negative pathogens can become resistant to most currently available antibiotics. Polymyxins have been revived as a last-line therapeutic option for the treatment of infections caused by multidrug-resistant Gra...

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Detalles Bibliográficos
Autores principales: Nang, Sue C., Azad, Mohammad A. K., Velkov, Tony, Zhou, Qi (Tony), Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911091/
https://www.ncbi.nlm.nih.gov/pubmed/33627412
http://dx.doi.org/10.1124/pharmrev.120.000020