JAK-STAT Pathway Inhibition Partially Restores Intestinal Homeostasis in Hdac1- and Hdac2-Intestinal Epithelial Cell-Deficient Mice

We have previously reported that histone deacetylase epigenetic regulator Hdac1 and Hdac2 deletion in intestinal epithelial cells (IEC) disrupts mucosal tissue architecture and barrier, causing chronic inflammation. In this study, proteome and transcriptome analysis revealed the importance of signal...

Descripción completa

Detalles Bibliográficos
Autores principales: Gonneaud, Alexis, Turgeon, Naomie, Boisvert, Francois-Michel, Boudreau, Francois, Asselin, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911100/
https://www.ncbi.nlm.nih.gov/pubmed/33498747
http://dx.doi.org/10.3390/cells10020224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911100/
https://www.ncbi.nlm.nih.gov/pubmed/33498747
http://dx.doi.org/10.3390/cells10020224

Ejemplares similares