The Protein-Binding Behavior of Platinum Anticancer Drugs in Blood Revealed by Mass Spectrometry

Cisplatin and its analogues are widely used as chemotherapeutic agents in clinical practice. After being intravenously administrated, a substantial amount of platinum will bind with proteins in the blood. This binding is vital for the transport, distribution, and metabolism of drugs; however, toxici...

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Detalles Bibliográficos
Autores principales: Wang, Jingchen, Tao, Jianmei, Jia, Shuailong, Wang, Meiqin, Jiang, Hongliang, Du, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911130/
https://www.ncbi.nlm.nih.gov/pubmed/33572935
http://dx.doi.org/10.3390/ph14020104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911130/
https://www.ncbi.nlm.nih.gov/pubmed/33572935
http://dx.doi.org/10.3390/ph14020104

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