HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy

The study describes the synthesis, physicochemical properties, and biological evaluation of polymer therapeutics based on N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers intended for a tumor-targeted immuno-oncotherapy. Water-soluble linear and cholesterol-containing HPMA precursors were synthes...

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Detalles Bibliográficos
Autores principales: Tavares, Marina R., Hrabánková, Klára, Konefał, Rafał, Kaňa, Martin, Říhová, Blanka, Etrych, Tomáš, Šírová, Milada, Chytil, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911143/
https://www.ncbi.nlm.nih.gov/pubmed/33525658
http://dx.doi.org/10.3390/pharmaceutics13020179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911143/
https://www.ncbi.nlm.nih.gov/pubmed/33525658
http://dx.doi.org/10.3390/pharmaceutics13020179

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