Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells

Calcitriol, a vitamin D(3) metabolite, is approved for various indications because it is the bioactive form of vitamin D in the body. The purpose of this study was to predict the clinical significance of cytochrome P450 (CYP) induction by calcitriol using in vitro human cryopreserved hepatocytes, He...

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Detalles Bibliográficos
Autores principales: Chae, Yoon-Jee, Kim, Min-Soo, Chung, Suk-Jae, Lee, Mi-Kyung, Lee, Kyeong-Ryoon, Maeng, Han-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911399/
https://www.ncbi.nlm.nih.gov/pubmed/33572963
http://dx.doi.org/10.3390/pharmaceutics13020181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911399/
https://www.ncbi.nlm.nih.gov/pubmed/33572963
http://dx.doi.org/10.3390/pharmaceutics13020181

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