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Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells

Calcitriol, a vitamin D(3) metabolite, is approved for various indications because it is the bioactive form of vitamin D in the body. The purpose of this study was to predict the clinical significance of cytochrome P450 (CYP) induction by calcitriol using in vitro human cryopreserved hepatocytes, He...

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Detalles Bibliográficos
Autores principales:	Chae, Yoon-Jee, Kim, Min-Soo, Chung, Suk-Jae, Lee, Mi-Kyung, Lee, Kyeong-Ryoon, Maeng, Han-Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911399/ https://www.ncbi.nlm.nih.gov/pubmed/33572963 http://dx.doi.org/10.3390/pharmaceutics13020181

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