A Rapid PCR-Free Next-Generation Sequencing Method for the Detection of Copy Number Variations in Prenatal Samples

Next-generation sequencing (NGS) is emerging as a new method for the detection of clinically significant copy number variants (CNVs). In this study, we developed and validated rapid CNV-sequencing (rCNV-seq) for clinical application in prenatal diagnosis. Low-pass whole-genome sequencing was perform...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xiya, Chen, Xiangbin, Jiang, Yulin, Qi, Qingwei, Hao, Na, Liu, Chengkun, Xu, Mengnan, Cram, David S., Liu, Juntao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911416/
https://www.ncbi.nlm.nih.gov/pubmed/33525582
http://dx.doi.org/10.3390/life11020098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911416/
https://www.ncbi.nlm.nih.gov/pubmed/33525582
http://dx.doi.org/10.3390/life11020098

Ejemplares similares