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Cdx2 Regulates Intestinal EphrinB1 through the Notch Pathway

The majority of colorectal cancers harbor loss-of-function mutations in APC, a negative regulator of canonical Wnt signaling, leading to intestinal polyps that are predisposed to malignant progression. Comparable murine APC alleles also evoke intestinal polyps, which are typically confined to the sm...

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Detalles Bibliográficos
Autores principales: Zhu, Yalun, Hryniuk, Alexa, Foley, Tanya, Hess, Bradley, Lohnes, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911442/
https://www.ncbi.nlm.nih.gov/pubmed/33525395
http://dx.doi.org/10.3390/genes12020188