Synthesis and Anticancer Activity of Hybrid Molecules Based on Lithocholic and (5Z,9Z)-Tetradeca-5,9-dienedioic Acids Linked via Mono(di,tri,tetra)ethylene Glycol and α,ω-Diaminoalkane Units

For the first time, hybrid molecules were synthesized on the basis of lithocholic and (5Z,9Z)-1,14-tetradeca-5,9-dienedicarboxylic acids, obtained in two stages using the homo-cyclomagnesiation reaction of 2-(hepta-5,6-diene-1-yloxy)tetrahydro-2H-pyran at the key stage. The resulting hybrid molecule...

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Detalles Bibliográficos
Autores principales: D’yakonov, Vladimir A., Tuktarova, Regina A., Dzhemileva, Lilya U., Ishmukhametova, Svetlana R., Dzhemilev, Usein M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911507/
https://www.ncbi.nlm.nih.gov/pubmed/33498764
http://dx.doi.org/10.3390/ph14020084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911507/
https://www.ncbi.nlm.nih.gov/pubmed/33498764
http://dx.doi.org/10.3390/ph14020084

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