Cargando…
Development of a Hierarchical Support Vector Regression-Based In Silico Model for Caco-2 Permeability
Drug absorption is one of the critical factors that should be taken into account in the process of drug discovery and development. The human colon carcinoma cell layer (Caco-2) model has been frequently used as a surrogate to preliminarily investigate the intestinal absorption. In this study, a quan...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911528/ https://www.ncbi.nlm.nih.gov/pubmed/33525340 http://dx.doi.org/10.3390/pharmaceutics13020174 |