Cargando…

Development of a Hierarchical Support Vector Regression-Based In Silico Model for Caco-2 Permeability

Drug absorption is one of the critical factors that should be taken into account in the process of drug discovery and development. The human colon carcinoma cell layer (Caco-2) model has been frequently used as a surrogate to preliminarily investigate the intestinal absorption. In this study, a quan...

Descripción completa

Detalles Bibliográficos
Autores principales: Ta, Giang Huong, Jhang, Cin-Syong, Weng, Ching-Feng, Leong, Max K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911528/
https://www.ncbi.nlm.nih.gov/pubmed/33525340
http://dx.doi.org/10.3390/pharmaceutics13020174