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Development of a Hierarchical Support Vector Regression-Based In Silico Model for Caco-2 Permeability
Drug absorption is one of the critical factors that should be taken into account in the process of drug discovery and development. The human colon carcinoma cell layer (Caco-2) model has been frequently used as a surrogate to preliminarily investigate the intestinal absorption. In this study, a quan...
Autores principales: | Ta, Giang Huong, Jhang, Cin-Syong, Weng, Ching-Feng, Leong, Max K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911528/ https://www.ncbi.nlm.nih.gov/pubmed/33525340 http://dx.doi.org/10.3390/pharmaceutics13020174 |
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