Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188

Viral proteases are critical enzymes for the maturation of many human pathogenic viruses and thus are key targets for direct acting antivirals (DAAs). The current viral pandemic caused by SARS-CoV-2 is in dire need of DAAs. The Main protease (M(pro)) is the focus of extensive structure-based drug de...

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Detalles Bibliográficos
Autores principales: Lockbaum, Gordon J., Reyes, Archie C., Lee, Jeong Min, Tilvawala, Ronak, Nalivaika, Ellen A., Ali, Akbar, Kurt Yilmaz, Nese, Thompson, Paul R., Schiffer, Celia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911568/
https://www.ncbi.nlm.nih.gov/pubmed/33503819
http://dx.doi.org/10.3390/v13020174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911568/
https://www.ncbi.nlm.nih.gov/pubmed/33503819
http://dx.doi.org/10.3390/v13020174

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