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Effect of An 84-bp Deletion of the Receptor-Binding Domain on the ACE2 Binding Affinity of the SARS-CoV-2 Spike Protein: An In Silico Analysis

SARS-CoV-2 is a recently emerged, novel human coronavirus responsible for the currently ongoing COVID-19 pandemic. Recombination is a well-known evolutionary strategy of coronaviruses, which may frequently result in significant genetic alterations, such as deletions throughout the genome. In this st...

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Detalles Bibliográficos
Autores principales: Kemenesi, Gábor, Tóth, Gábor Endre, Bajusz, Dávid, Keserű, György M., Terhes, Gabriella, Burián, Katalin, Zeghbib, Safia, Somogyi, Balázs A., Jakab, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911659/
https://www.ncbi.nlm.nih.gov/pubmed/33572725
http://dx.doi.org/10.3390/genes12020194